Depressive Symptoms, Telomere Length and Bladder Cancer
نویسندگان
چکیده
1 Depressive Symptoms and Short Telomere Length Are Associated with Increased Mortality in Bladder Cancer Patients Jie Lin,* Janice A. Blalock,* Meng Chen, Yuanqing Ye, Jian Gu, Lorenzo Cohen, Paul M. Cinciripini, Xifeng Wu Departments of Epidemiology, 1155 Pressler, Unit Number 1340, Houston, TX 77030; Behavioral Science, 1155 Pressler, Unit Number 1330, Houston, TX 77030; General Oncology and the Integrative Medicine Program, 1515 Holcombe Blvd., Unit 0462, Houston, TX 77030, The University of Texas MD Anderson Cancer Center *Co-first authors; Co-last authors Correspondence to: Lorenzo Cohen, PhD, Department of General Oncology, Integrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, Texas, 1515 Holcombe Blvd, Unit 0462, Houston, Texas 77030, USA. Telephone: 713/745-4260. Fax: 713/745-4286. e-mail: [email protected]. Previously presented at Eleventh Annual American Association for Cancer Research International Conference on Frontiers in Cancer Prevention Research, Anaheim, CA, 10/2012 The authors declare no conflict of interests.
منابع مشابه
Depressive symptoms and short telomere length are associated with increased mortality in bladder cancer patients.
BACKGROUND Depression is associated with an increased risk of mortality in patients with cancer; it has been hypothesized that depression-associated alterations in cell aging mechanisms, in particular, the telomere/telomerase maintenance system, may underlie this increased risk. We evaluated the association of depressive symptoms and telomere length to mortality and recurrence/progression in 46...
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OBJECTIVE Psychological factors such as the stress of caregiving are emerging as predictors of telomere length, an index of biological aging. However, although lifetime major depressive disorder is associated with shorter telomeres, less is known about depressive symptoms. Depression and depressive symptoms are associated with a range of morbidities and mortality, but the extent to which they p...
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